[^~\x22]+

.*

Ignore strings that start with the label “abc_”.

Use a negative look-ahead assertion:

^(?!abc_).+

Or, use a negative look-behind assertion:

(^.{1,3}$|^.{4}(?<!abc_).*)

Or, use plain old character sets and alternations:

^([^a]|a($|[^b]|b($|[^c]|c($|[^_])))).*

Use a negative lookbehind assertion:

^[/\w\.-]+(?<!\.html)$

or, use a lookahead:

^(?!.*\.html$)[/\w\.-]+$

https://www.regular-expressions.info/lookaround.html